Chandra Study of X-Ray Point Sources in the Early-Type Galaxy NGC 4552 (M89)

We present a Chandra ACIS study of the early-type galaxy NGC 4552. We detect 47 X-ray point sources, most of which are likely LMXBs, within 4 R_e. The brightest X-ray source coincides with the optical/UV/radio center of the galaxy, and shows variability on >1 hr timescales, indicating the possible existence of a LLAGN. The 46 off-center sources and the unresolved point sources contribute about 29% and 20% to the total luminosity of the galaxy, respectively. The corrected cumulative XLF of the off-center sources is best fit by a broken power-law model with a break at L_b=4.4+2.0-1.4 e38 ergs/s. We identified 210 GCs candidates in a HST WFPC2 optical image of the galaxy's central region. Of the 25 off-center LMXBs that fall within the WFPC2 FOV, 10 sources are coincident with a GC. Thus the fraction of the GCs hosting bright LMXBs and the fraction of the LMXBs associated with GCs are 4.8% and 40%, respectively. In the V and I bands, the GCs hosting bright LMXBs are typically 1-2 magnitudes brighter than the GCs with no detected LMXBs. There are about 1.9+-0.4 times as many LMXBs in the red, metal-rich GCs as there are in the blue, metal-poor ones. We find no obvious difference between the luminosity distributions of LMXBs in GCs and in field, but the cumulative spectrum of the LMXBs in GCs tends to be softer than that of the LMXBs in field. We detected 3 X-ray sources that have isotropic luminosities larger than 1e39 erg/s. The one located in the joint Chandra-HST field is found to be associated with a GC. By studying the ACIS spectra we infer that the this may be a candidate black hole system with a mass of 15-135 M_sun. One of the other sources with a luminosity brighter than 1e39 ergs/s reveals temporal variations in brightness on timescales greater than an hour.Comment: Accepted for publication in Ap

Research progress on antidepressant effects and mechanisms of berberine

Depression, a global health problem with growing prevalence, brings serious impacts on the daily life of patients. However, the antidepressants currently used in clinical are not perfectly effective, which greatly reduces the compliance of patients. Berberine is a natural quaternary alkaloid which has been shown to have a variety of pharmacological effects, such as hypoglycemic, lipid-regulation, anti-cancer, antibacterial, anti-oxidation, anti-inflammatory, and antidepressant. This review summarizes the evidence of pharmacological applications of berberine in treating depression and elucidates the mechanisms of berberine regulating neurotransmitter levels, promoting the regeneration of hippocampal neurons, improving hypothalamic-pituitary-adrenal axis dysfunction, anti-oxidative stress, and suppressing inflammatory status in order to provide a reference for further research and clinical application of berberine

Psychometric Properties of the Chinese SUPPS-P Impulsive Behavior Scale: Factor Structure and Measurement Invariance Across Gender and Age

Objective: Impulsivity is widely recognized as a risk factor for a variety of mental disorders and problematic behaviors. The Short UPPS-P Impulsive Behavior Scale (SUPPS-P) is an extensively used instrument to measure impulsivity in research and clinical settings. The current study primarily aimed to evaluate the psychometric properties of the Chinese version of the SUPPS-P (C-SUPPS-P) among Chinese adolescents and emerging adults, and then to test its measurement invariance across gender and age. Methods: Data were collected from three vocational high schools and six colleges in Changsha, China. A total of 2,551 participants (20.1% male and 22.6% adolescents) completed the C-SUPPS-P and scales assessing addictive and problematic smartphone use, as well as emotional symptoms (anxiety, stress, depression). Four alternative models were examined and compared by using confirmatory factor analysis to determine the best factor structure of the C-SUPPS-P. Multigroup confirmatory factor analyses were used to test measurement invariance across gender and age. Results: A theory-driven five-factor structure consistent with the original scale was identified. All of the subscales had good internal consistency. The correlations observed with the other scales supported the construct validity of the C-SUPPS-P. Full measurement invariance was established across gender and age, and significant gender and age differences according to impulsivity facets were identified. Conclusions: The C-SUPPS-P presents a consistent factor structure, as well as reliability and validity that are equivalent to those of the original scale. The full measurement invariance shown across gender and age allows for intergroup comparisons. Overall, the C-SUPPS-P is a promising instrument to measure various impulsivity traits in Chinese adolescents and emerging adults

Chandra Observation of the Cluster of Galaxies MS 0839.9+2938 at z=0.194: the Central Excess Iron and SN Ia Enrichment

We present the Chandra study of the intermediately distant cluster of galaxies MS 0839.9+2938. By performing both the projected and deprojected spectral analyses, we find that the gas temperature is approximately constant at about 4 keV in 130-444h_70^-1 kpc. In the inner regions, the gas temperature descends towards the center, reaching <~ 3 keV in the central 37h_70^-1 kpc. This infers that the lower and upper limits of the mass deposit rate are 9-34 M_sun yr^-1 and 96-126 M_sun yr^-1, respectively within 74h_70^-1 kpc where the gas is significantly colder. Along with the temperature drop, we detect a significant inward iron abundance increase from about 0.4 solar in the outer regions to about 1 solar within the central 37h_70^-1 kpc. Thus MS 0839.9+2938 is the cluster showing the most significant central iron excess at z>~ 0.2. We argue that most of the excess iron should have been contributed by SNe Ia. By utilizing the observed SN Ia rate and stellar mass loss rate, we estimate that the time needed to enrich the central region with excess iron is 6.4-7.9 Gyr, which is similar to those found for the nearby clusters. Coinciding with the optical extension of the cD galaxy (up to about 30h_70^-1 kpc), the observed X-ray surface brightness profile exhibits an excess beyond the distribution expected by either the beta model or the NFW model, and can be well fitted with an empirical two-beta model that leads to a relatively flatter mass profile in the innermost region.Comment: Accepted for publication in Ap